Hybridtides® are a new class of drug candidates that deliver unique product profiles.
Oral Peptide Delivery
Hybridtides® demonstrate robust durability in a variety of biological matrices. Absorption parameters are optimized via our proprietary databases.
The unique composition of Hybridtides® (natural and non-natural amino acids) enables 'fine-tuning' of intracellular signal cascades. In other words, Hybridtides® demonstrate signal bias.
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Philadelphia, PA 19104
Investors & Support
Developing breakthrough therapeutics based on the Hybridtide® peptide scaffold
Hybridtide Optimization Toolkit
If your preclinical peptide program requires demonstrated market leading stability in any biological environment – without compromising functionality – contact us, Hybridtides® can deliver your product profile.
Oral Peptide Platform
Formulation alone is not sufficient for commercial success, API’s require a combination of stability, solubility and absorption. Our team can evaluate your program across these critical parameters (in vitro and in vivo) and can help optimize your program along these critical dimensions for oral delivery.
Hybridtides can modulate molecular biology pathways (e.g. cAMP, β-Arrestin1 & β-Arrestin2) independent of each other in addition to targeting different states of a protein (e.g. open vs. closed). These features are critical for intracellular targeting, delivery or binding affinity tuning. Contact us to learn more.